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At this time, there are two ongoing studies (TAKL and HARP), one research pilot (FRESH AIR), one audit, one multi-partner study about to start (UBIOPRED), one study (HEALTH) that was finished early due to recruitment difficulties and one completed and published project (antibiotic prescribing).
- The HARP Study (ongoing)
IPCRG has provided a grant to Optimum Patient Care to further develop a website for patients that not only provides them with personalised feedback on their asthma health, but enables results to be transferred to their physician, to encourage consultations that are relevant and helpful to the individual patient. It will also provide a basis for use of the website in other languages. Funded by the UKRRF
- The ICAPP study (Improving Asthma Care in Portuguese Patients) (ongoing)
IPCRG have provided a grant to Universidade do Minho for Dr Jaime Correia de Sousa and Dr John Yaphe to undertake research on the following questions: Does improved recording of asthma care using items from the IPCRG guidelines improve the outcomes of asthma control for patients? and Are patient compliance, concordance and enablement associated with better asthma control and outcomes?
- The TAKL Study (ongoing)
The TAKL Study: An Investigation of the Safety and Efficacy of Oral AKL1 in Patients Diagnosed with Obstructive Lung Disease. This is a Phase II trial led by Dr Andrew Wilson of the University of East Anglia. It is an extension of the DDX trial in asthma previously undertaken by Dr Mike Thomas at Aberdeen. Funded by the UKRRF Press coverage (copy on word file)
- FRESH AIR (pilot underway in Vietnam)
Effectiveness and cost-benefit of case-finding, smoking cessation and indoor biomass smoke-reduction strategies in resource limited primary care settings. This is being piloted in Vietnam, as part of the e-faculty programme. Pictured right is Niels Chavannes, the main researcher, with the Vietnamese team including Prof Lan and Dr Vinh.
- The HEALTH Study (finished early)
The Health Enhancing Physical Activity Lung Therapy (HEALTH) Study was a randomised controlled trial (RCT) carried out in conjunction with the University of Exeter. It aimed to determine the additional effects of a physical activity programme on physiological and psychological outcomes in participants with mild COPD who were receiving optimal bronchodilation using tiotropium, in accordance with guidelines from the National Institute for Health and Clinical Excellence (NICE). It was finished early due to recruitment difficulties. See Faulkner J, Walshaw E, Campbell J, Jones R, Taylor R, Price D, Taylor AH. The feasibility of recruiting patients with early COPD to a pilot trial assessing the effects of a physical activity intervention. Prim Care Resp J 2010; Available from: URL: http://dx.doi.org/10.4104/pcrj.2010.00008
- U-BIOPRED study
The IPCRG is one of 41 partners across Europe participating in the U-BIOPRED study led by Dr Peter Sterk (Unbiased BIOmarkers used for PREDicting disease progression and medication efficacy in severe asthma) that has just been selected for funding by the European Union Innovative Medicines Initiative. Our role is in Ethics & Safety and Dissemination. 13/6/2010. An article that outlines the U-BIOPRED approach has been published in Chest. "An Integrative Systems Biology Approach to Understanding Pulmonary Diseases"
- Uncontrolled Asthma Audit
This new audit on management of uncontrolled asthma aims to provide information on how patients with asthma exacerbations are managed in ‘real life’.
- Risk Factors for Adverse Outcomes of Lower Respiratory Tract Infection Diagnosed in UK General Practice (completed)
This observational study aimed to investigate the role of antibiotics in the management of LRTI in UK primary care. The study is now published in Chest 2009 and online November 2008. Key findings: Antibiotic prescribing on the day of LRTI diagnosis was associated with reductions in admissions and mortality related to respiratory infection. Antibiotics may help to prevent adverse outcomes for some patients with LRTI. (Winchester CC, et al. Antibiotic prescribing and outcomes of lower respiratory tract infection in UK primary care. doi:10.1378/chest.08-2940).
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